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Associations of depression and anxiety with cardiovascular risk among people living with HIV/AIDS in Korea
Kyong Sil Park, Seon Young Hwang, Bo Youl Choi, June Kim, Sang Il Kim, Woo-Joo Kim, Chun Kang
Epidemiol Health. 2021;43:e2021002.   Published online December 24, 2020
DOI: https://doi.org/10.4178/epih.e2021002
  • 12,952 View
  • 384 Download
  • 2 Web of Science
  • 3 Crossref
AbstractAbstract AbstractSummary PDFSupplementary Material
Abstract
OBJECTIVES
As HIV/AIDS is becoming a chronic disease, the risk of developing cardiovascular disease (CVD) among people living with HIV/AIDS is rising. Anxiety and depression, which are common among people living with HIV/AIDS, have been linked with CVD. This study investigated the risk of CVD in people living with HIV/AIDS and explored the effects of depression and anxiety on CVD risk.
METHODS
Data were collected for 457 people enrolled in the Korea Cohort HIV/AIDS study after 2010. Framingham risk scores were calculated to quantify the 10-year risk of developing CVD. Depression and anxiety variables were re-coded as a single combined variable. Multivariable logistic regression analysis was performed, adjusting for age, body mass index, low-density lipoprotein (LDL) cholesterol, triglycerides (TG), duration of human immunodeficiency virus (HIV) positivity after entry into the cohort, and depression/anxiety.
RESULTS
Participants with both depression and anxiety were 2.28 times more likely than those with neither depression nor anxiety to have moderate/high-risk CVD risk. The 10-year risk of developing CVD was affected by LDL cholesterol, TG, age, and duration of HIV infection. LDL cholesterol and TG levels change according to the duration of HIV infection, and metabolic disorders affect the risk of CVD. Thus, a longer duration of HIV infection is associated with a higher risk of developing CVD.
CONCLUSIONS
Screenings for depression and anxiety need to be provided regularly to assess the severity of those symptoms. To help decrease their risk of developing CVD, people living with HIV/AIDS should be offered behavioral modification interventions aimed at developing healthy lifestyle habits.
Summary
Korean summary
본 연구를 통해 우울과 불안이 심혈관질환 발생위험을 증가시키는 영향요인임을 확인하였다. 따라서, HIV 감염자의 우울과 불안에 대한 정기적인 검사 및 상담이 필요하며, 우울 또는 불안한 환자의 심혈관질환의 발병 위험을 줄이기위해 좋은 생활 습관을 위한 행동 수정 및 동기 부여 교육프로그램의 개발이 필요하다.
Key Message
healthcare providers need to provide motivational education for behavioral modifications to decrease patients’ risk of developing CVD, especially among those with depression or anxiety symptoms.

Citations

Citations to this article as recorded by  
  • Comorbidities among persons living with HIV (PLWH) in Florida: a network analysis
    Shyfuddin Ahmed, Angel B. Algarin, Hsu Thadar, Zhi Zhou, Tanjila Taskin, Krishna Vaddiparti, Karina Villalba, Yan Wang, Nicole Ennis, Jamie P. Morano, Charurut Somboonwit, Robert L Cook, Gladys E. Ibañez
    AIDS Care.2023; 35(7): 1055.     CrossRef
  • Elevated frequency and everyday functioning implications of vascular depression in persons with HIV disease
    Ilex Beltran-Najera, Andrea Mustafa, Desmond Warren, Zach Salling, Maria Misiura, Steven Paul Woods, Vonetta M. Dotson
    Journal of Psychiatric Research.2023; 160: 78.     CrossRef
  • MENTE X CORAÇÃO: AS DOENÇAS PSIQUICAS E AS CONSENQUÊNCIAS CARDIOVASCULARES: UMA REVISÃO DA LITERATURA
    Beatriz da Silva Araújo, Morgana Gonçalves da Silva
    Revista interdisciplinar em saúde.2021; 8(Único): 292.     CrossRef
Lifestyle-related predictors affecting prediabetes and diabetes in 20-30-year-old young Korean adults
Kyong Sil Park, Seon Young Hwang
Epidemiol Health. 2020;42:e2020014.   Published online March 19, 2020
DOI: https://doi.org/10.4178/epih.e2020014
  • 12,396 View
  • 279 Download
  • 4 Web of Science
  • 6 Crossref
AbstractAbstract AbstractSummary PDFSupplementary Material
Abstract
OBJECTIVES
To investigate lifestyle-related predictors of prediabetes and diabetes in young adults aged 20–39 years using data from the 2014-2016 Korea National Health and Nutrition Examination Survey (KNHANES).
METHODS
This study is a cross-sectional, secondary analysis using the KNHANES data. Participants were classified into normal group (fasting plasma glucose [FPG] <100 mg/dL and/or hemoglobin A1c [HbA1c] <5.7%), prediabetes group (FPG 100-125 mg/dL and/or HbA1c 5.7-6.4%), and diabetes group (FPG ≥126 mg/dL and/or HbA1c ≥ 6.5%). The data were statistically analyzed using SPSS software.
RESULTS
Out of 4,190 participants, 27.7% of men and 16.3% of women were in the prediabetes group and 1.4% of men and 1.3% of women were in the diabetes group. Logistic regression confirmed that age and obesity are predictors of prediabetes and diabetes in both men and women. Additionally low physical activity and low education level are predictors of prediabetes in men and women, respectively (p<0.05).
CONCLUSIONS
This study has found that age and increased obesity are predictors of elevated blood glucose in young men and women in their 20s and 30s. A strategy to lower obesity by promoting physical activity in men in their 30s is essential to prevent metabolic syndrome and progression to prediabetes.
Summary
Korean summary
20-30대 젊은 성인 남성에서 당뇨전단계 27.7%, 당뇨 1.4%, 여성에서 당뇨전단계 16.4%, 당뇨 1.3%로 확인되었다. 당뇨전단계 및 당뇨의 이환을 예방하기 위해서 비만 관리가 필수적이며, 특히 교육수준이 낮은 젊은 여성과 신체활동이 낮은 30대의 남성에서 신체활동 증진을 통해 효율적으로 비만도를 낮추는 전략 마련이 필요함을 확인하였다.

Citations

Citations to this article as recorded by  
  • Effects of a Remote Physical Activity Improvement Program on Male Office Workers with Metabolic Syndrome in Their 30s and 40s with Sedentary Behavior: A Randomized Controlled Trial
    Kyong Sil Park, Seon Young Hwang
    Asian Nursing Research.2024;[Epub]     CrossRef
  • Prediabetes and all-cause mortality in young patients undergoing coronary artery angiography: a multicenter cohort study in China
    Yibo He, Hongyu Lu, Yihang Ling, Jin Liu, Sijia Yu, Ziyou Zhou, Tian Chang, Yong Liu, Shiqun Chen, Jiyan Chen
    Cardiovascular Diabetology.2023;[Epub]     CrossRef
  • A Study Analyzing the Relationship among Impaired Fasting Glucose (IFG), Obesity Index, Physical Activity, and Beverage and Alcohol Consumption Frequency in 20s and 30s:The Korea National Health and Nutrition Examination Survey (KNHANES) 2013-2015
    Yujin Lee, Jung-Hyun Kim
    The Korean Journal of Community Living Science.2022; 33(1): 19.     CrossRef
  • Sex differences in factors associated with prediabetes in Korean adults
    Jin Suk Ra
    Osong Public Health and Research Perspectives.2022; 13(2): 142.     CrossRef
  • Differences in health behavior and nutrient intake status between diabetes-aware and unaware Korean adults based on the Korea national health and nutrition examination survey 2016–18 data: A cross-sectional study
    Anshul Sharma, Chen Lulu, Kee-Ho Song, Hae-Jeung Lee
    Frontiers in Public Health.2022;[Epub]     CrossRef
  • Mediterranean Diet and Healthy Eating in Subjects with Prediabetes from the Mollerussa Prospective Observational Cohort Study
    Mireia Falguera, Esmeralda Castelblanco, Marina Idalia Rojo-López, Maria Belén Vilanova, Jordi Real, Nuria Alcubierre, Neus Miró, Àngels Molló, Manel Mata-Cases, Josep Franch-Nadal, Minerva Granado-Casas, Didac Mauricio
    Nutrients.2021; 13(1): 252.     CrossRef

Epidemiol Health : Epidemiology and Health